KABUL, Afghanistan — An American national working for the United Nations in Afghanistan was killed and two others were wounded in a blast targeting a U.N. vehicle in Kabul on Sunday, officials said, underscoring a growing threat to aid workers.

The attack led U.N. agencies in Afghanistan to impose lockdowns on Monday, while other major international organizations restricted their movements as a precaution. Officials said the U.N. also canceled flights, even though many smaller aid organizations rely on air travel to get to parts of the country not accessible by roads increasingly plagued by fighting.

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